Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1350 aa)    
Predicted Functional Partners:
DAXX
Death domain-associated protein 6 isoform X2.
    
 0.996
DAB2IP
Disabled homolog 2-interacting protein isoform X1.
    
 0.988
MAP2K4
Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
    
 0.986
ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1.
    
 0.983
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.978
MAP2K6
Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily.
    
 0.974
MAP2K3
Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.
    
 0.974
TXN2
Thioredoxin, mitochondrial.
    
 0.973
PARK7
Protein/nucleic acid deglycase DJ-1.
    
 0.970
MAP2K7
Dual specificity mitogen-activated protein kinase kinase 7 isoform X2.
    
 0.960
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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