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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL6A3Collagen alpha-3(VI) chain isoform X2. (1715 aa)    
Predicted Functional Partners:
COL6A3-2
Collagen alpha-3(VI) chain isoform X1.
 
     0.925
COL6A2
Collagen alpha-2(VI) chain.
   
0.766
COL1A2
Collagen alpha-2(I) chain.
   
 
0.695
COL6A1
Collagen alpha-1(VI) chain.
   
0.694
COL1A1
Collagen alpha-1(I) chain.
   
 
0.657
CUNH9orf116
UPF0691 protein C9orf116 homolog isoform X1.
   
   0.617
TEKT3
Tektin-3.
   
   0.592
CATIP
Ciliogenesis-associated TTC17-interacting protein.
   
    0.590
COL5A2
Collagen alpha-2(V) chain.
   
 
0.557
LUM
Lumican.
   
 0.522
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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