Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Experiments
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[Homology]
Score
GNA14Guanine nucleotide-binding protein subunit alpha-14. (365 aa)    
Predicted Functional Partners:
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.960
TBXA2R
Thromboxane A2 receptor.
    
 0.950
CCKBR
Gastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.946
AGTR1
Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.941
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.941
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.935
CCKAR
Cholecystokinin receptor type A isoform X2; Belongs to the G-protein coupled receptor 1 family.
    
 0.929
EDNRB
Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.
   
 0.922
EDNRA
Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.
   
 0.920
F2R
Proteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.915
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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