close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)    
Predicted Functional Partners:
ENSVVUP00000004411
annotation not available
    
 0.922
FADD
FAS-associated death domain protein.
    
 0.876
CASP8
Caspase-8; Belongs to the peptidase C14A family.
   
 0.804
CASP10
Caspase-10; Belongs to the peptidase C14A family.
   
 0.779
CFLAR
CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family.
   
 0.752
RIPK1
Receptor-interacting serine/threonine-protein kinase 1.
    
 0.718
FAS
Tumor necrosis factor receptor superfamily member 6.
     
 0.650
TNFRSF11B
Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
      
 0.640
FASLG
Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family.
     
0.616
CASP3
Caspase-3 isoform X1; Belongs to the peptidase C14A family.
   
 0.573
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.