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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)    
Predicted Functional Partners:
SKP2
S-phase kinase-associated protein 2.
   
 0.987
CUL1
Cullin-1; Belongs to the cullin family.
    
 0.973
SKP1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.971
RBX1
E3 ubiquitin-protein ligase RBX1 isoform X2.
   
 0.940
CKS1B
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
  
  
 
0.901
CCNA2
cyclin-A2; Belongs to the cyclin family.
   
 0.860
CDK2
Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily.
   
 0.858
CCNA1
cyclin-A1 isoform X1; Belongs to the cyclin family.
   
 0.840
CDK1
LOW QUALITY PROTEIN: cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.781
ENSVVUP00000012585
annotation not available
   
 0.781
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.