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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXB1Forkhead box protein B1. (325 aa)    
Predicted Functional Partners:
SOX5
Transcription factor SOX-5 isoform X5.
      
 0.755
PRDM16
PR domain zinc finger protein 16.
      
 0.657
CFAP36
Cilia- and flagella-associated protein 36.
      
 0.607
FAM81B
Protein FAM81B.
      
 0.604
HOMEZ
Homeobox and leucine zipper protein Homez.
      
 0.603
SHOX
Short stature homeobox protein.
   
  
 0.547
SHOX2
Short stature homeobox protein 2.
   
  
 0.542
PKNOX2
Homeobox protein PKNOX2 isoform X1.
      
 0.524
BUB3
Mitotic checkpoint protein BUB3 isoform X2.
      
 0.519
XPR1
Xenotropic and polytropic retrovirus receptor 1.
      
 0.499
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.