close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCG8ATP-binding cassette sub-family G member 8. (690 aa)    
Predicted Functional Partners:
ABCG5
ATP-binding cassette sub-family G member 5.
  
0.999
NPC1L1
NPC1-like intracellular cholesterol transporter 1 isoform X1.
   
 
 0.720
SORCS1
VPS10 domain-containing receptor SorCS1.
      
 0.665
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 
 0.657
APOB
Apolipoprotein B-100.
   
  
 0.642
NR1H3
Oxysterols receptor LXR-alpha.
   
 0.637
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
      
 0.604
GTF2IRD1
General transcription factor II-I repeat domain-containing protein 1 isoform X1.
      
 0.567
NR1H4
Bile acid receptor isoform X2.
   
 0.565
RABEP2
Rab GTPase-binding effector protein 2.
      
 0.554
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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