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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RORANuclear receptor ROR-alpha. (473 aa)    
Predicted Functional Partners:
GRM1
Metabotropic glutamate receptor 1 isoform X1.
   
 
 0.934
RORB
Nuclear receptor ROR-beta isoform X1.
  
 
0.918
ITPR1-2
Inositol 1,4,5-trisphosphate receptor type 1.
     
 0.904
ATP2A2
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
     
 0.903
TRPC3
Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family.
     
  0.900
SLC1A6
Amino acid transporter.
     
  0.900
ATP2A1
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
     
  0.900
KAT5
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
     
 0.848
NRIP1
Nuclear receptor-interacting protein 1.
    
 0.826
NCOR2
Nuclear receptor corepressor 2 isoform X9.
    
 0.680
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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