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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPP1R11E3 ubiquitin-protein ligase PPP1R11. (126 aa)    
Predicted Functional Partners:
PPP1R7
Protein phosphatase 1 regulatory subunit 7 isoform X1.
   
 
 0.951
ENSVVUP00000002212
annotation not available
   
 
 0.717
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 
 0.717
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 
 0.717
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 
 0.717
NSFL1C
NSFL1 cofactor p47.
   
 
 0.635
UBXN2B
UBX domain-containing protein 2B.
   
 
 0.632
GNL1
Guanine nucleotide-binding protein-like 1.
      
 0.613
TRIM26
Tripartite motif-containing protein 26 isoform X2.
      
 0.607
REEP4
Receptor expression-enhancing protein.
   
  
 0.607
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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