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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSDL2Hydroxysteroid dehydrogenase-like protein 2. (418 aa)    
Predicted Functional Partners:
ECI2
enoyl-CoA delta isomerase 2, mitochondrial.
  
 0.888
ACAA1
3-ketoacyl-CoA thiolase, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.884
HADHB
Trifunctional enzyme subunit beta, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.875
ACAA2
3-ketoacyl-CoA thiolase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.873
ADHFE1
Hydroxyacid-oxoacid transhydrogenase, mitochondrial.
  
 0.863
PEX5L
PEX5-related protein isoform X1.
   
 0.861
ACAT2
acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.861
CARTPT
Cocaine- and amphetamine-regulated transcript protein.
  
 0.861
PEX5
Peroxisomal biogenesis factor 5 isoform X1.
   
 0.861
ACAT1
acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.861
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.