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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB7BZinc finger and BTB domain-containing protein 7B. (531 aa)    
Predicted Functional Partners:
DNTT
DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.
    
 
 0.728
RAB25
Ras-related protein Rab-25 isoform X2.
    
 0.630
HNRNPU
Heterogeneous nuclear ribonucleoprotein U isoform X2.
   
 
 0.495
RUNX3
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
    
 0.473
SOX13
Transcription factor SOX-13 isoform X4.
    
 
 0.471
NKX2-4
Homeobox protein Nkx-2.4.
    
 
 0.465
TMPO
Thymopoietin isoform X1.
    
 0.465
VOPP1
VOPP1 WW domain binding protein.
      
 0.442
NKX2-8
Homeobox protein Nkx-2.8.
      
 0.442
ITPKB
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.441
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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