Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDN2LOW QUALITY PROTEIN: endothelin-2. (188 aa)    
Predicted Functional Partners:
EDNRA
Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.
     
 0.966
EDNRB
Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.
     
 0.957
OXTR
Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
     
 0.924
EDN1
Endothelin-1.
   
 
 0.908
EDN3
Endothelin-3 isoform X1.
     
 0.902
HTR1F
LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 1F.
     
 0.900
HTR1E
5-hydroxytryptamine receptor 1E.
     
 0.900
DRD2
D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family.
     
 0.900
HTR1D
5-hydroxytryptamine receptor 1D.
     
 0.900
SSTR1
Somatostatin receptor type 1 isoform X1; Belongs to the G-protein coupled receptor 1 family.
     
 0.897
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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