TOLLIP protein (Vulpes vulpes) - STRING interaction network

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Score

TOLLIP

Toll-interacting protein isoform X1. (274 aa)

Predicted Functional Partners:

MYD88

0.978

IRAK4

0.957

TLR2

0.949

IRAK1

0.941

TIRAP

0.884

TOM1

0.869

IRAK2

0.811

TRAF6

0.779

SIGIRR

0.717

IL1B

0.716

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL1B	IRAK1	ENSVVUP00000040168	ENSVVUP00000041587	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1 receptor-associated kinase 1.	0.752
IL1B	IRAK2	ENSVVUP00000040168	ENSVVUP00000032260	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1 receptor-associated kinase-like 2.	0.624
IL1B	IRAK4	ENSVVUP00000040168	ENSVVUP00000023148	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1 receptor-associated kinase 4.	0.782
IL1B	MYD88	ENSVVUP00000040168	ENSVVUP00000008136	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.881
IL1B	TIRAP	ENSVVUP00000040168	ENSVVUP00000027359	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Toll/interleukin-1 receptor domain-containing adapter protein.	0.456
IL1B	TLR2	ENSVVUP00000040168	ENSVVUP00000034657	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Toll-like receptor 2; Belongs to the Toll-like receptor family.	0.776
IL1B	TOLLIP	ENSVVUP00000040168	ENSVVUP00000002677	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Toll-interacting protein isoform X1.	0.716
IL1B	TRAF6	ENSVVUP00000040168	ENSVVUP00000009350	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.841
IRAK1	IL1B	ENSVVUP00000041587	ENSVVUP00000040168	Interleukin-1 receptor-associated kinase 1.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.752
IRAK1	IRAK2	ENSVVUP00000041587	ENSVVUP00000032260	Interleukin-1 receptor-associated kinase 1.	Interleukin-1 receptor-associated kinase-like 2.	0.898
IRAK1	IRAK4	ENSVVUP00000041587	ENSVVUP00000023148	Interleukin-1 receptor-associated kinase 1.	Interleukin-1 receptor-associated kinase 4.	0.999
IRAK1	MYD88	ENSVVUP00000041587	ENSVVUP00000008136	Interleukin-1 receptor-associated kinase 1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.999
IRAK1	SIGIRR	ENSVVUP00000041587	ENSVVUP00000023258	Interleukin-1 receptor-associated kinase 1.	Single Ig IL-1-related receptor isoform X1.	0.479
IRAK1	TIRAP	ENSVVUP00000041587	ENSVVUP00000027359	Interleukin-1 receptor-associated kinase 1.	Toll/interleukin-1 receptor domain-containing adapter protein.	0.966
IRAK1	TLR2	ENSVVUP00000041587	ENSVVUP00000034657	Interleukin-1 receptor-associated kinase 1.	Toll-like receptor 2; Belongs to the Toll-like receptor family.	0.623
IRAK1	TOLLIP	ENSVVUP00000041587	ENSVVUP00000002677	Interleukin-1 receptor-associated kinase 1.	Toll-interacting protein isoform X1.	0.941
IRAK1	TRAF6	ENSVVUP00000041587	ENSVVUP00000009350	Interleukin-1 receptor-associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
IRAK2	IL1B	ENSVVUP00000032260	ENSVVUP00000040168	Interleukin-1 receptor-associated kinase-like 2.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.624
IRAK2	IRAK1	ENSVVUP00000032260	ENSVVUP00000041587	Interleukin-1 receptor-associated kinase-like 2.	Interleukin-1 receptor-associated kinase 1.	0.898
IRAK2	IRAK4	ENSVVUP00000032260	ENSVVUP00000023148	Interleukin-1 receptor-associated kinase-like 2.	Interleukin-1 receptor-associated kinase 4.	0.987