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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC33Tetratricopeptide repeat protein 33 isoform X1. (506 aa)    
Predicted Functional Partners:
LEO1
RNA polymerase-associated protein LEO1.
    
 0.814
GET4
Golgi to ER traffic protein 4 homolog isoform X1.
   
 0.743
PSME3IP1
Protein FAM192A.
      
 0.725
SEC61B
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
 0.682
RAD23A
UV excision repair protein RAD23 homolog A isoform X1.
   
 0.648
RAD23B
UV excision repair protein RAD23 homolog B.
   
 0.648
METTL21A
Protein N-lysine methyltransferase METTL21A isoform X1.
    
 
 0.621
FASTKD2
FAST kinase domain-containing protein 2, mitochondrial.
      
 0.604
ENSVVUP00000021839
annotation not available
   
 0.599
GET3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
   
 0.599
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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