Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DAB2Disabled homolog 2 isoform X1. (873 aa)    
Predicted Functional Partners:
MYO6
Unconventional myosin-VI isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.960
LRP2
Low-density lipoprotein receptor-related protein 2.
    
 0.960
LDLR
Low-density lipoprotein receptor.
    
 0.928
LDLRAP1
Low density lipoprotein receptor adapter protein 1.
     
 0.923
GRB2
Growth factor receptor-bound protein 2.
   
 0.914
CLTB
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.874
ITSN2
Intersectin-2 isoform X4.
    
 0.860
FCHO2
F-BAR domain only protein 2 isoform X1.
   
 0.844
FCHO1
F-BAR domain only protein 1 isoform X2.
   
 0.844
EPS15L1
Epidermal growth factor receptor substrate 15-like 1 isoform X2.
    
 0.834
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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