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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF185E3 ubiquitin-protein ligase RNF185. (187 aa)    
Predicted Functional Partners:
ERLIN1
Erlin-1.
   
 0.877
ERLIN2
Erlin-2 isoform X1.
   
 0.832
TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1.
    
 
 0.785
TMEM259
Membralin.
    
 
 0.777
TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2 isoform X1.
    
 
 0.771
C6orf120
UPF0669 protein C6orf120 homolog.
      
 0.751
HERPUD2
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein.
      
 0.738
UBE2J1
Ubiquitin-conjugating enzyme E2 J1.
    
 
 0.737
FAM8A1
Protein FAM8A1.
      
 0.734
NPLOC4
Nuclear protein localization protein 4 homolog.
   
  
 0.717
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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