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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF654Zinc finger protein 654 isoform X1. (1170 aa)    
Predicted Functional Partners:
LTN1
E3 ubiquitin-protein ligase listerin.
   
 
  0.642
VSIG10
V-set and immunoglobulin domain-containing protein 10 isoform X1.
      
 0.550
LRRC1
Leucine-rich repeat-containing protein 1 isoform X1.
    
 0.539
RCAN3
Calcipressin-3.
      
 0.516
TMEM120B
Transmembrane protein 120B isoform X2.
      
 0.505
PPFIA4
Liprin-alpha-4.
      
 0.501
LOC112914300
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-like isoform X1.
      
 0.497
CCDC6
Coiled-coil domain-containing protein 6.
    
 
 0.457
DDX58
Probable ATP-dependent RNA helicase DDX58.
    
 
 0.424
AMOTL1
Angiomotin-like protein 1 isoform X1.
    
 0.402
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.