ENSVVUP00000003179 protein (Vulpes vulpes) - STRING interaction network

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Score

ENSVVUP00000003179

annotation not available (825 aa)

Predicted Functional Partners:

NTHL1

0.573

PCNA

0.561

MYRF-2

0.520

SNRPD3

0.520

LIG1

0.497

MUTYH

0.480

OGG1

0.480

SNRPD1

0.436

LSM10

0.436

TDG

0.418

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSVVUP00000003179	LIG1	ENSVVUP00000003179	ENSVVUP00000032128	annotation not available	DNA ligase.	0.497
ENSVVUP00000003179	LSM10	ENSVVUP00000003179	ENSVVUP00000031960	annotation not available	U7 snRNA-associated Sm-like protein LSm10.	0.436
ENSVVUP00000003179	MUTYH	ENSVVUP00000003179	ENSVVUP00000010126	annotation not available	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.480
ENSVVUP00000003179	MYRF-2	ENSVVUP00000003179	ENSVVUP00000005331	annotation not available	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.520
ENSVVUP00000003179	NTHL1	ENSVVUP00000003179	ENSVVUP00000012983	annotation not available	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.573
ENSVVUP00000003179	OGG1	ENSVVUP00000003179	ENSVVUP00000032819	annotation not available	N-glycosylase/DNA lyase isoform X1.	0.480
ENSVVUP00000003179	PCNA	ENSVVUP00000003179	ENSVVUP00000033727	annotation not available	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.561
ENSVVUP00000003179	SNRPD1	ENSVVUP00000003179	ENSVVUP00000005104	annotation not available	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.	0.436
ENSVVUP00000003179	SNRPD3	ENSVVUP00000003179	ENSVVUP00000026351	annotation not available	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.	0.520
ENSVVUP00000003179	TDG	ENSVVUP00000003179	ENSVVUP00000023907	annotation not available	G/T mismatch-specific thymine DNA glycosylase.	0.418
LIG1	ENSVVUP00000003179	ENSVVUP00000032128	ENSVVUP00000003179	DNA ligase.	annotation not available	0.497
LIG1	MYRF-2	ENSVVUP00000032128	ENSVVUP00000005331	DNA ligase.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.976
LIG1	NTHL1	ENSVVUP00000032128	ENSVVUP00000012983	DNA ligase.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.478
LIG1	OGG1	ENSVVUP00000032128	ENSVVUP00000032819	DNA ligase.	N-glycosylase/DNA lyase isoform X1.	0.634
LIG1	PCNA	ENSVVUP00000032128	ENSVVUP00000033727	DNA ligase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.994
LIG1	TDG	ENSVVUP00000032128	ENSVVUP00000023907	DNA ligase.	G/T mismatch-specific thymine DNA glycosylase.	0.634
LSM10	ENSVVUP00000003179	ENSVVUP00000031960	ENSVVUP00000003179	U7 snRNA-associated Sm-like protein LSm10.	annotation not available	0.436
LSM10	SNRPD1	ENSVVUP00000031960	ENSVVUP00000005104	U7 snRNA-associated Sm-like protein LSm10.	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.	0.439
LSM10	SNRPD3	ENSVVUP00000031960	ENSVVUP00000026351	U7 snRNA-associated Sm-like protein LSm10.	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.	0.996
MUTYH	ENSVVUP00000003179	ENSVVUP00000010126	ENSVVUP00000003179	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	annotation not available	0.480