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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDP2tyrosyl-DNA phosphodiesterase 2. (180 aa)    
Predicted Functional Partners:
TDP1
tyrosyl-DNA phosphodiesterase 1.
   
  
 0.758
RAD23A
UV excision repair protein RAD23 homolog A isoform X1.
    
 
 0.617
EMG1
Ribosomal RNA small subunit methyltransferase NEP1.
      
 0.610
YPEL3
Protein yippee-like; Belongs to the yippee family.
      
 0.610
MLH3
DNA mismatch repair protein Mlh3 isoform X1.
      
 0.607
SPRTN
sprT-like domain-containing protein Spartan isoform X1.
      
 0.607
ZNF398
Zinc finger protein 398 isoform X1.
      
 0.607
RPS27A
ubiquitin-40S ribosomal protein S27a.
    
 
 0.602
ENSVVUP00000014764
annotation not available
    
 
 0.602
UBA52
ubiquitin-60S ribosomal protein L40.
    
   0.599
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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