Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ATXN7L2Ataxin-7-like protein 2 isoform X3. (695 aa)    
Predicted Functional Partners:
ATXN7L3
Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]
    
 0.975
TADA2B
Transcriptional adapter.
    
 0.931
TRRAP
Transformation/transcription domain-associated protein isoform X2; Belongs to the PI3/PI4-kinase family.
    
 0.929
SGF29
SAGA-associated factor 29 isoform X1.
    
 0.867
TAF10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
    
 0.826
TADA2A
Transcriptional adapter.
    
 0.822
TAF9B
Transcription initiation factor TFIID subunit 9B.
    
 0.792
TAF9
Transcription initiation factor TFIID subunit 9.
    
 0.787
LOC112907387
Transcription initiation factor TFIID subunit 9-like.
    
 0.787
ENSVVUP00000016731
annotation not available
    
 0.784
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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