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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIFRLeukemia inhibitory factor receptor. (1148 aa)    
Predicted Functional Partners:
LIF
Leukemia inhibitory factor.
    
 0.988
OSM
oncostatin-M.
    
 0.984
CTF1
LOW QUALITY PROTEIN: cardiotrophin-1.
    
 0.980
JAK1
Tyrosine-protein kinase.
    
 0.967
JAK2
Tyrosine-protein kinase.
    
 0.964
CLCF1
Cardiotrophin-like cytokine factor 1.
     
 0.959
CNTFR
Ciliary neurotrophic factor receptor subunit alpha.
    
 0.957
IL6ST
Interleukin-6 receptor subunit beta isoform X1.
   
0.957
JAK3
Tyrosine-protein kinase.
    
 0.946
LOC112914774
Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1.
     
 0.916
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.