TSG101 protein (Vulpes vulpes) - STRING interaction network

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[Homology]

Score

TSG101

LOW QUALITY PROTEIN: tumor susceptibility gene 101 protein. (373 aa)

Predicted Functional Partners:

VPS28

0.990

HGS

0.962

VPS37B

0.960

MVB12A

0.935

MVB12B

0.929

VPS36

0.914

VPS37A

0.909

PDCD6IP

0.858

CEP55

0.829

VPS37C

0.828

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEP55	MVB12A	ENSVVUP00000030189	ENSVVUP00000021912	Centrosomal protein of 55 kDa.	Multivesicular body subunit 12A isoform X1.	0.549
CEP55	PDCD6IP	ENSVVUP00000030189	ENSVVUP00000030217	Centrosomal protein of 55 kDa.	Programmed cell death 6-interacting protein isoform X2.	0.746
CEP55	TSG101	ENSVVUP00000030189	ENSVVUP00000003418	Centrosomal protein of 55 kDa.	LOW QUALITY PROTEIN: tumor susceptibility gene 101 protein.	0.829
CEP55	VPS28	ENSVVUP00000030189	ENSVVUP00000007862	Centrosomal protein of 55 kDa.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.636
HGS	MVB12A	ENSVVUP00000027209	ENSVVUP00000021912	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Multivesicular body subunit 12A isoform X1.	0.620
HGS	MVB12B	ENSVVUP00000027209	ENSVVUP00000013967	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Multivesicular body subunit 12B isoform X2.	0.640
HGS	PDCD6IP	ENSVVUP00000027209	ENSVVUP00000030217	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Programmed cell death 6-interacting protein isoform X2.	0.523
HGS	TSG101	ENSVVUP00000027209	ENSVVUP00000003418	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	LOW QUALITY PROTEIN: tumor susceptibility gene 101 protein.	0.962
HGS	VPS28	ENSVVUP00000027209	ENSVVUP00000007862	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.776
HGS	VPS36	ENSVVUP00000027209	ENSVVUP00000037450	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Vacuolar protein-sorting-associated protein 36 isoform X2.	0.734
HGS	VPS37A	ENSVVUP00000027209	ENSVVUP00000010035	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Vacuolar protein sorting-associated protein 37A isoform X1.	0.611
HGS	VPS37B	ENSVVUP00000027209	ENSVVUP00000039430	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Vacuolar protein sorting-associated protein 37B.	0.702
HGS	VPS37C	ENSVVUP00000027209	ENSVVUP00000006512	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Vacuolar protein sorting-associated protein 37C isoform X1.	0.637
MVB12A	CEP55	ENSVVUP00000021912	ENSVVUP00000030189	Multivesicular body subunit 12A isoform X1.	Centrosomal protein of 55 kDa.	0.549
MVB12A	HGS	ENSVVUP00000021912	ENSVVUP00000027209	Multivesicular body subunit 12A isoform X1.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.620
MVB12A	MVB12B	ENSVVUP00000021912	ENSVVUP00000013967	Multivesicular body subunit 12A isoform X1.	Multivesicular body subunit 12B isoform X2.	0.678
MVB12A	PDCD6IP	ENSVVUP00000021912	ENSVVUP00000030217	Multivesicular body subunit 12A isoform X1.	Programmed cell death 6-interacting protein isoform X2.	0.948
MVB12A	TSG101	ENSVVUP00000021912	ENSVVUP00000003418	Multivesicular body subunit 12A isoform X1.	LOW QUALITY PROTEIN: tumor susceptibility gene 101 protein.	0.935
MVB12A	VPS28	ENSVVUP00000021912	ENSVVUP00000007862	Multivesicular body subunit 12A isoform X1.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.993
MVB12A	VPS36	ENSVVUP00000021912	ENSVVUP00000037450	Multivesicular body subunit 12A isoform X1.	Vacuolar protein-sorting-associated protein 36 isoform X2.	0.829