INS protein (Vulpes vulpes) - STRING interaction network

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INS

Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)

Predicted Functional Partners:

INSR

0.999

IGF1R

0.997

INSRR

0.987

EGF

0.985

IDE

0.984

IGF1

0.980

IRS1

0.968

GHRL

0.965

EGFR

0.964

IRS4

0.959

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	EGFR	ENSVVUP00000024040	ENSVVUP00000013448	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.999
EGF	IGF1	ENSVVUP00000024040	ENSVVUP00000024480	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin-like growth factor I isoform X1.	0.971
EGF	IGF1R	ENSVVUP00000024040	ENSVVUP00000019227	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.954
EGF	INS	ENSVVUP00000024040	ENSVVUP00000003455	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.985
EGF	INSR	ENSVVUP00000024040	ENSVVUP00000039649	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.940
EGF	INSRR	ENSVVUP00000024040	ENSVVUP00000008195	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.777
EGFR	EGF	ENSVVUP00000013448	ENSVVUP00000024040	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.999
EGFR	IGF1	ENSVVUP00000013448	ENSVVUP00000024480	Receptor protein-tyrosine kinase.	Insulin-like growth factor I isoform X1.	0.950
EGFR	IGF1R	ENSVVUP00000013448	ENSVVUP00000019227	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.960
EGFR	INS	ENSVVUP00000013448	ENSVVUP00000003455	Receptor protein-tyrosine kinase.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.964
EGFR	INSR	ENSVVUP00000013448	ENSVVUP00000039649	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.940
EGFR	IRS1	ENSVVUP00000013448	ENSVVUP00000035996	Receptor protein-tyrosine kinase.	Insulin receptor substrate 1.	0.759
GHRL	IGF1	ENSVVUP00000032234	ENSVVUP00000024480	Appetite-regulating hormone isoform X1.	Insulin-like growth factor I isoform X1.	0.929
GHRL	INS	ENSVVUP00000032234	ENSVVUP00000003455	Appetite-regulating hormone isoform X1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.965
IDE	INS	ENSVVUP00000029815	ENSVVUP00000003455	Insulin-degrading enzyme isoform X1; Belongs to the peptidase M16 family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.984
IGF1	EGF	ENSVVUP00000024480	ENSVVUP00000024040	Insulin-like growth factor I isoform X1.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.971
IGF1	EGFR	ENSVVUP00000024480	ENSVVUP00000013448	Insulin-like growth factor I isoform X1.	Receptor protein-tyrosine kinase.	0.950
IGF1	GHRL	ENSVVUP00000024480	ENSVVUP00000032234	Insulin-like growth factor I isoform X1.	Appetite-regulating hormone isoform X1.	0.929
IGF1	IGF1R	ENSVVUP00000024480	ENSVVUP00000019227	Insulin-like growth factor I isoform X1.	Tyrosine-protein kinase receptor.	0.999
IGF1	INS	ENSVVUP00000024480	ENSVVUP00000003455	Insulin-like growth factor I isoform X1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.980

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