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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STK36Serine/threonine-protein kinase 36 isoform X2. (1316 aa)    
Predicted Functional Partners:
SUFU
Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...]
    
 0.960
KIF27
Kinesin-like protein KIF27; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.874
KIF7
LOW QUALITY PROTEIN: kinesin-like protein KIF7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.817
KIF21B
Kinesin-like protein KIF21B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.809
ENSVVUP00000001613
annotation not available
   
 0.809
SMO
Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.764
GLI1
Zinc finger protein GLI1.
    
 0.749
DPCD
Protein DPCD isoform X1.
      
 0.739
ZNF142
Zinc finger protein 142.
    
 0.725
CFP
Properdin.
      
 0.725
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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