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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASCL2Achaete-scute homolog 2. (197 aa)    
Predicted Functional Partners:
LGR5
Leucine-rich repeat-containing G-protein coupled receptor 5.
      
 0.819
OLFM4
Olfactomedin-4.
      
 0.813
LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1.
   
  
 0.752
TCF4
Transcription factor 4 isoform X1.
   
 0.715
ENSVVUP00000001275
annotation not available
   
 0.664
TCF12
Transcription factor 12 isoform X2.
   
 0.664
LOC112912783
Transcription factor E2-alpha-like.
   
 0.636
TCF3
Transcription factor E2-alpha.
   
 0.636
AXIN2
Axin-2 isoform X1.
      
 0.603
HOPX
Homeodomain-only protein.
    
 0.579
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.