URB1 protein (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

URB1

Nucleolar pre-ribosomal-associated protein 1 isoform X1. (2268 aa)

Predicted Functional Partners:

PDCD11

0.914

POLR1B

0.881

HEATR1

0.859

UTP20

0.834

NAT10

0.822

WDR36

0.822

LOC112909567

0.822

POLR1A

0.816

DDX24

0.803

UTP4

0.789

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX24	HEATR1	ENSVVUP00000025445	ENSVVUP00000012793	ATP-dependent RNA helicase DDX24.	HEAT repeat-containing protein 1 isoform X1.	0.827
DDX24	LOC112909567	ENSVVUP00000025445	ENSVVUP00000033814	ATP-dependent RNA helicase DDX24.	Periodic tryptophan protein 2 homolog.	0.830
DDX24	NAT10	ENSVVUP00000025445	ENSVVUP00000013925	ATP-dependent RNA helicase DDX24.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.818
DDX24	PDCD11	ENSVVUP00000025445	ENSVVUP00000005703	ATP-dependent RNA helicase DDX24.	Protein RRP5 homolog.	0.904
DDX24	POLR1A	ENSVVUP00000025445	ENSVVUP00000001532	ATP-dependent RNA helicase DDX24.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.546
DDX24	POLR1B	ENSVVUP00000025445	ENSVVUP00000040148	ATP-dependent RNA helicase DDX24.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.659
DDX24	URB1	ENSVVUP00000025445	ENSVVUP00000003619	ATP-dependent RNA helicase DDX24.	Nucleolar pre-ribosomal-associated protein 1 isoform X1.	0.803
DDX24	UTP20	ENSVVUP00000025445	ENSVVUP00000025163	ATP-dependent RNA helicase DDX24.	Small subunit processome component 20 homolog.	0.727
DDX24	UTP4	ENSVVUP00000025445	ENSVVUP00000017969	ATP-dependent RNA helicase DDX24.	U3 small nucleolar RNA-associated protein 4 homolog isoform X2.	0.643
DDX24	WDR36	ENSVVUP00000025445	ENSVVUP00000017407	ATP-dependent RNA helicase DDX24.	WD repeat-containing protein 36.	0.669
HEATR1	DDX24	ENSVVUP00000012793	ENSVVUP00000025445	HEAT repeat-containing protein 1 isoform X1.	ATP-dependent RNA helicase DDX24.	0.827
HEATR1	LOC112909567	ENSVVUP00000012793	ENSVVUP00000033814	HEAT repeat-containing protein 1 isoform X1.	Periodic tryptophan protein 2 homolog.	0.998
HEATR1	NAT10	ENSVVUP00000012793	ENSVVUP00000013925	HEAT repeat-containing protein 1 isoform X1.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.990
HEATR1	PDCD11	ENSVVUP00000012793	ENSVVUP00000005703	HEAT repeat-containing protein 1 isoform X1.	Protein RRP5 homolog.	0.998
HEATR1	POLR1A	ENSVVUP00000012793	ENSVVUP00000001532	HEAT repeat-containing protein 1 isoform X1.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.920
HEATR1	POLR1B	ENSVVUP00000012793	ENSVVUP00000040148	HEAT repeat-containing protein 1 isoform X1.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.849
HEATR1	URB1	ENSVVUP00000012793	ENSVVUP00000003619	HEAT repeat-containing protein 1 isoform X1.	Nucleolar pre-ribosomal-associated protein 1 isoform X1.	0.859
HEATR1	UTP20	ENSVVUP00000012793	ENSVVUP00000025163	HEAT repeat-containing protein 1 isoform X1.	Small subunit processome component 20 homolog.	0.998
HEATR1	UTP4	ENSVVUP00000012793	ENSVVUP00000017969	HEAT repeat-containing protein 1 isoform X1.	U3 small nucleolar RNA-associated protein 4 homolog isoform X2.	0.999
HEATR1	WDR36	ENSVVUP00000012793	ENSVVUP00000017407	HEAT repeat-containing protein 1 isoform X1.	WD repeat-containing protein 36.	0.998