PITX3 protein (Vulpes vulpes) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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Score

PITX3

Homeobox protein. (302 aa)

Predicted Functional Partners:

WNT1

0.715

GJA3

0.607

GJA8

0.607

BFSP1

0.607

TH

0.605

SLC18A2

0.553

CRYAA

0.528

CRYBB2

0.527

FGF8

0.523

LIM2

0.523

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BFSP1	CRYAA	ENSVVUP00000019112	ENSVVUP00000023508	Filensin.	Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	0.872
BFSP1	CRYBB2	ENSVVUP00000019112	ENSVVUP00000021760	Filensin.	Beta-crystallin B2; Belongs to the beta/gamma-crystallin family.	0.791
BFSP1	GJA3	ENSVVUP00000019112	ENSVVUP00000008664	Filensin.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.622
BFSP1	GJA8	ENSVVUP00000019112	ENSVVUP00000009995	Filensin.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.813
BFSP1	LIM2	ENSVVUP00000019112	ENSVVUP00000015361	Filensin.	Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family.	0.538
BFSP1	PITX3	ENSVVUP00000019112	ENSVVUP00000003630	Filensin.	Homeobox protein.	0.607
CRYAA	BFSP1	ENSVVUP00000023508	ENSVVUP00000019112	Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	Filensin.	0.872
CRYAA	CRYBB2	ENSVVUP00000023508	ENSVVUP00000021760	Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	Beta-crystallin B2; Belongs to the beta/gamma-crystallin family.	0.870
CRYAA	GJA3	ENSVVUP00000023508	ENSVVUP00000008664	Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.610
CRYAA	GJA8	ENSVVUP00000023508	ENSVVUP00000009995	Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.696
CRYAA	LIM2	ENSVVUP00000023508	ENSVVUP00000015361	Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family.	0.552
CRYAA	PITX3	ENSVVUP00000023508	ENSVVUP00000003630	Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	Homeobox protein.	0.528
CRYBB2	BFSP1	ENSVVUP00000021760	ENSVVUP00000019112	Beta-crystallin B2; Belongs to the beta/gamma-crystallin family.	Filensin.	0.791
CRYBB2	CRYAA	ENSVVUP00000021760	ENSVVUP00000023508	Beta-crystallin B2; Belongs to the beta/gamma-crystallin family.	Alpha-crystallin A chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.	0.870
CRYBB2	GJA3	ENSVVUP00000021760	ENSVVUP00000008664	Beta-crystallin B2; Belongs to the beta/gamma-crystallin family.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.683
CRYBB2	GJA8	ENSVVUP00000021760	ENSVVUP00000009995	Beta-crystallin B2; Belongs to the beta/gamma-crystallin family.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.722
CRYBB2	LIM2	ENSVVUP00000021760	ENSVVUP00000015361	Beta-crystallin B2; Belongs to the beta/gamma-crystallin family.	Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family.	0.574
CRYBB2	PITX3	ENSVVUP00000021760	ENSVVUP00000003630	Beta-crystallin B2; Belongs to the beta/gamma-crystallin family.	Homeobox protein.	0.527
FGF8	PITX3	ENSVVUP00000001072	ENSVVUP00000003630	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox protein.	0.523
FGF8	TH	ENSVVUP00000001072	ENSVVUP00000003525	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Tyrosine 3-monooxygenase isoform X1.	0.517