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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPS8L3Epidermal growth factor receptor kinase substrate 8-like protein 3. (727 aa)    
Predicted Functional Partners:
CASK
Peripheral plasma membrane protein CASK isoform X5; Belongs to the MAGUK family.
    
 0.699
TWF2
Twinfilin-2 isoform X1.
     
 0.640
AXDND1
Axonemal dynein light chain domain-containing protein 1.
      
 0.639
SLC45A4
Solute carrier family 45 member 4.
      
 0.634
USH1C
Harmonin isoform X1.
   
 
 0.630
APCDD1
Protein APCDD1 isoform X1.
      
 0.614
LPAR6
Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.612
CDSN
Corneodesmosin.
   
  
 0.611
TWF1
Twinfilin-1.
     
 0.610
DSG4
Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
      
 0.607
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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