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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCN2Connective tissue growth factor. (464 aa)    
Predicted Functional Partners:
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
   
  
 0.782
COL1A1
Collagen alpha-1(I) chain.
   
  
 0.743
SMAD2
Mothers against decapentaplegic homolog.
   
  
 0.700
SRF
Serum response factor isoform X1.
      
 0.700
SMAD3
Mothers against decapentaplegic homolog.
   
  
 0.699
LATS1
Serine/threonine-protein kinase LATS1 isoform X1.
      
 0.695
YAP1
Transcriptional coactivator YAP1.
   
 0.660
SERPINE1
Plasminogen activator inhibitor 1; Belongs to the serpin family.
   
 
 0.655
COL1A2
Collagen alpha-2(I) chain.
   
  
 0.652
ANKRD1
Ankyrin repeat domain-containing protein 1.
   
 
 0.649
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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