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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (326 aa)    
Predicted Functional Partners:
CCS
Copper chaperone for superoxide dismutase.
  
0.995
SOD2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.994
BCL2
Apoptosis regulator Bcl-2.
    
 0.970
PARK7
Protein/nucleic acid deglycase DJ-1.
  
 0.959
PPARGC1A
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1.
     
 0.947
HSPA5
Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.
   
 0.943
VDAC1
Voltage-dependent anion-selective channel protein 1 isoform X1.
   
 
 0.934
C9orf72
Guanine nucleotide exchange C9orf72 homolog.
      
 0.930
NEFL
Neurofilament light polypeptide; Belongs to the intermediate filament family.
     
 0.921
PPP3R2
Calcineurin subunit B type 2.
    
 0.919
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.