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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOVA2RNA-binding protein Nova-2. (216 aa)    
Predicted Functional Partners:
SRRM4
Serine/arginine repetitive matrix protein 4.
      
 0.537
MEX3B
RNA-binding protein MEX3B.
    
 
 0.505
TREM2
Triggering receptor expressed on myeloid cells 2 isoform X1.
   
  
 0.485
PTBP2
Polypyrimidine tract-binding protein 2 isoform X3.
    
 
 0.475
DLG3
Disks large homolog 3 isoform X2; Belongs to the MAGUK family.
      
 0.457
PRSS53
Serine protease 53 isoform X2; Belongs to the peptidase S1 family.
      
 0.453
ENSVVUP00000017790
annotation not available
   
  
 0.444
CELF3
CUGBP Elav-like family member 3 isoform X1.
   
  
 0.444
DNM1
Dynamin-1 isoform X9; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
  
 0.444
CELF4
CUGBP Elav-like family member 4 isoform X6.
   
  
 0.444
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.