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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRPM5Transient receptor potential cation channel subfamily M member 5. (1182 aa)    
Predicted Functional Partners:
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 
 0.880
TAS1R3
Taste receptor type 1 member 3.
      
 0.830
PKD2L1
Polycystic kidney disease 2-like 1 protein isoform X1.
   
 
 0.801
ASCL3
Achaete-scute homolog 3.
      
 0.789
POU2F3
POU domain protein.
    
 
 0.785
CALHM1
Calcium homeostasis modulator protein 1.
      
 0.772
DCLK1-2
Serine/threonine-protein kinase DCLK1 isoform X7.
      
 0.769
TAS1R1
Taste receptor type 1 member 1.
      
 0.763
TAS1R2
Taste receptor type 1 member 2.
      
 0.755
GNAT3
Guanine nucleotide-binding protein G(T) subunit alpha-3.
      
 0.750
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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