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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF25E3 ubiquitin-protein ligase RNF25 isoform X1. (470 aa)    
Predicted Functional Partners:
LSM7
U6 snRNA-associated Sm-like protein LSm7.
      
 0.723
RNF11
RING finger protein 11.
      
 0.709
MINK1
Misshapen-like kinase 1 isoform X6.
      
 0.614
PSME1
Proteasome activator complex subunit 1.
      
 0.610
PSMB4
Proteasome subunit beta; Belongs to the peptidase T1B family.
      
 0.607
ABI2
Abl interactor 2 isoform X4.
      
 0.607
GIT2
ARF GTPase-activating protein GIT2 isoform X2.
      
 0.603
PSMA6
Proteasome subunit alpha type.
      
 0.603
ENSVVUP00000027737
annotation not available
      
 0.603
SNAPIN
SNARE-associated protein Snapin.
      
 0.603
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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