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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MGST1Microsomal glutathione S-transferase 1. (180 aa)    
Predicted Functional Partners:
MGST3
Microsomal glutathione S-transferase 3.
   
 
 0.955
EPHX1
Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.
   
 
 0.930
PRDX6
Peroxiredoxin-6.
   
 
 0.920
MGST2
Microsomal glutathione S-transferase 2.
    
 0.917
GSR
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
 0.912
GSS
Glutathione synthetase.
     
 0.910
TXNDC12
Thioredoxin domain-containing protein 12.
     
 0.906
CYP1A1
Cytochrome P450 1A1; Belongs to the cytochrome P450 family.
     
 0.906
CYP1B1
Cytochrome P450 1B1; Belongs to the cytochrome P450 family.
     
 0.906
CYP1A2
Cytochrome P450 1A2 isoform X2; Belongs to the cytochrome P450 family.
     
 0.903
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.