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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SP2Transcription factor Sp2 isoform X1. (614 aa)    
Predicted Functional Partners:
ZNF263
Zinc finger protein 263 isoform X1.
    
 
0.640
WAC
WW domain-containing adapter protein with coiled-coil isoform X2.
    
 
 0.610
CDR2
Cerebellar degeneration-related protein 2.
      
 0.607
RS1
Retinoschisin.
    
 
 0.607
PLPP7
Inactive phospholipid phosphatase 7.
      
 0.607
RP2
Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
      
 0.605
FLI1
Friend leukemia integration 1 transcription factor isoform X2.
    
 
 0.603
FANCD2OS
FANCD2 opposite strand protein.
      
 0.556
KSR2
Kinase suppressor of Ras 2 isoform X1.
    
 0.537
HM13
Minor histocompatibility antigen H13 isoform X2.
      
 0.485
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.