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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTNNA2Catenin alpha-2 isoform X1. (728 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta-1 isoform X1.
   
 0.990
CDH1
Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.963
ACTN1
Alpha-actinin-1.
   
 0.927
ACTN4
Alpha-actinin-4 isoform X3.
   
 0.926
TJP1
Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family.
   
 0.919
YWHAH
14-3-3 protein eta; Belongs to the 14-3-3 family.
     
 0.919
ENSVVUP00000004152
annotation not available
 
     0.917
YWHAE
14-3-3 protein epsilon isoform X3; Belongs to the 14-3-3 family.
     
 0.917
YWHAG
14-3-3 protein gamma; Belongs to the 14-3-3 family.
     
 0.917
YWHAQ
14-3-3 protein theta; Belongs to the 14-3-3 family.
     
 0.914
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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