close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BSPRYB box and SPRY domain-containing protein. (348 aa)    
Predicted Functional Partners:
WNK3
Serine/threonine-protein kinase WNK3.
      
 0.740
TRPV5
Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.607
TRPV6
Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.605
SLC31A2
Probable low affinity copper uptake protein 2 isoform X1.
      
 0.555
COPS5
COP9 signalosome complex subunit 5 isoform X1.
    
 
 0.522
ALAD
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
      
 0.516
RGS2
Regulator of G-protein signaling 2.
    
 
 0.514
RNF183
Probable E3 ubiquitin-protein ligase RNF183 isoform X1.
    
 
 0.500
C9orf43
Uncharacterized protein C9orf43 homolog.
      
 0.497
EMC8
ER membrane protein complex subunit 8 isoform X2.
      
 0.463
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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