| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSS1 | ADSS2 | ENSVVUP00000004046 | ENSVVUP00000037053 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
| ADSS1 | DOHH | ENSVVUP00000004046 | ENSVVUP00000004162 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | 0.726 |
| ADSS1 | EIF5A | ENSVVUP00000004046 | ENSVVUP00000039014 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Eukaryotic translation initiation factor 5A. | 0.441 |
| ADSS1 | EIF5A2 | ENSVVUP00000004046 | ENSVVUP00000001396 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Eukaryotic translation initiation factor 5A. | 0.441 |
| ADSS1 | LOC112923709 | ENSVVUP00000004046 | ENSVVUP00000007994 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein LOC112923709 isoform X1. | 0.741 |
| ADSS2 | ADSS1 | ENSVVUP00000037053 | ENSVVUP00000004046 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
| ADSS2 | DOHH | ENSVVUP00000037053 | ENSVVUP00000004162 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | 0.726 |
| ADSS2 | EIF5A | ENSVVUP00000037053 | ENSVVUP00000039014 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Eukaryotic translation initiation factor 5A. | 0.441 |
| ADSS2 | EIF5A2 | ENSVVUP00000037053 | ENSVVUP00000001396 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Eukaryotic translation initiation factor 5A. | 0.441 |
| ADSS2 | LOC112923709 | ENSVVUP00000037053 | ENSVVUP00000007994 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein LOC112923709 isoform X1. | 0.741 |
| DHPS | DOHH | ENSVVUP00000032958 | ENSVVUP00000004162 | Deoxyhypusine synthase isoform X1. | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | 0.948 |
| DHPS | EIF5A | ENSVVUP00000032958 | ENSVVUP00000039014 | Deoxyhypusine synthase isoform X1. | Eukaryotic translation initiation factor 5A. | 0.989 |
| DHPS | EIF5A2 | ENSVVUP00000032958 | ENSVVUP00000001396 | Deoxyhypusine synthase isoform X1. | Eukaryotic translation initiation factor 5A. | 0.989 |
| DOHH | ADSS1 | ENSVVUP00000004162 | ENSVVUP00000004046 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.726 |
| DOHH | ADSS2 | ENSVVUP00000004162 | ENSVVUP00000037053 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.726 |
| DOHH | DHPS | ENSVVUP00000004162 | ENSVVUP00000032958 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Deoxyhypusine synthase isoform X1. | 0.948 |
| DOHH | EIF5A | ENSVVUP00000004162 | ENSVVUP00000039014 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Eukaryotic translation initiation factor 5A. | 0.982 |
| DOHH | EIF5A2 | ENSVVUP00000004162 | ENSVVUP00000001396 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Eukaryotic translation initiation factor 5A. | 0.979 |
| DOHH | FH | ENSVVUP00000004162 | ENSVVUP00000036897 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Fumarate hydratase, mitochondrial. | 0.757 |
| DOHH | GPD2 | ENSVVUP00000004162 | ENSVVUP00000027913 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. | Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.763 |
STRING v12.5 is now available!
