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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (200 aa)    
Predicted Functional Partners:
GPC1
Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.932
FN1
Fibronectin.
     
 0.924
SDC4
Syndecan-4.
     
0.921
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
0.917
EZR
Ezrin isoform X1.
     
  0.900
RDX
Radixin isoform X1.
     
  0.900
MSN
Moesin.
     
  0.900
SDC1
Syndecan 1.
  
  
0.780
VTN
Vitronectin.
     
 0.585
TRPC7
Short transient receptor potential channel 7; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.580
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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