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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAD51BDNA repair protein RAD51 homolog 2 isoform X3. (271 aa)    
Predicted Functional Partners:
XRCC2
DNA repair protein XRCC2.
   
0.994
RAD51C
DNA repair protein RAD51 homolog 3 isoform X1.
   
0.985
RAD51D
DNA repair protein RAD51 homolog 4 isoform X1.
   
0.980
WRN
Werner syndrome ATP-dependent helicase.
  
 0.976
XRCC3
DNA repair protein XRCC3.
  
 
0.945
BRCA2
Breast cancer type 2 susceptibility protein.
   
 0.943
FANCM
Fanconi anemia group M protein.
   
 0.928
EXO1
Exonuclease 1.
  
 0.880
RAD52
DNA repair protein RAD52 homolog.
    
 0.877
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.864
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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