Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAD51BDNA repair protein RAD51 homolog 2 isoform X3. (271 aa)    
Predicted Functional Partners:
XRCC2
DNA repair protein XRCC2.
   
0.998
RAD51C
DNA repair protein RAD51 homolog 3 isoform X1.
   
0.997
RAD51D
DNA repair protein RAD51 homolog 4 isoform X1.
   
0.995
XRCC3
DNA repair protein XRCC3.
  
 
0.951
BRCA2
Breast cancer type 2 susceptibility protein.
   
 0.948
WRN
Werner syndrome ATP-dependent helicase.
   
 0.947
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
    
 0.922
FANCM
Fanconi anemia group M protein.
   
 0.906
RAD50
DNA repair protein RAD50 isoform X1.
   
 0.900
EXO1
Exonuclease 1.
  
 0.882
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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