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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMC1Transmembrane channel-like protein. (720 aa)    
Predicted Functional Partners:
CIB2
Calcium and integrin-binding family member 2 isoform X1.
    
 0.928
LHFPL5
LHFPL tetraspan subfamily member 5 protein isoform X1.
   
 
 0.915
CIB3
Calcium and integrin-binding family member 3 isoform X1.
    
 0.866
CIB1
Calcium and integrin-binding protein 1.
    
 0.818
TMIE
Transmembrane inner ear expressed protein.
   
 
 0.788
MYO7A
Unconventional myosin-VIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.777
SLC26A5
Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
   
 
 0.752
USH1C
Harmonin isoform X1.
    
 
 0.724
WHRN
Whirlin.
    
 
 0.709
PCDH15
Protocadherin-15.
    
 0.704
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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