close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC112912892Hepcidin. (85 aa)    
Predicted Functional Partners:
SLC40A1
Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
    
 
 0.833
LCN2
LOW QUALITY PROTEIN: neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family.
   
 
 0.736
HFE
Hereditary hemochromatosis protein; Belongs to the MHC class I family.
   
  
 0.702
TFR2
Transferrin receptor protein 2 isoform X1.
      
 0.695
HJV
Hemojuvelin isoform X4.
      
 0.606
KRTAP8-1
Keratin-associated protein 8-1.
   
    0.554
SLC11A2
Natural resistance-associated macrophage protein 2 isoform X2.
      
 0.518
HEPH
Hephaestin isoform X1; Belongs to the multicopper oxidase family.
      
 0.497
TFRC
Transferrin receptor protein 1.
      
 0.495
TMPRSS6
Transmembrane protease serine 6; Belongs to the peptidase S1 family.
      
 0.493
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.