| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACLY | ACO1 | ENSVVUP00000026024 | ENSVVUP00000028932 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | 0.970 |
| ACLY | ACO2 | ENSVVUP00000026024 | ENSVVUP00000004610 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.971 |
| ACLY | CS | ENSVVUP00000026024 | ENSVVUP00000030054 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Citrate synthase; Belongs to the citrate synthase family. | 0.995 |
| ACLY | IDH1 | ENSVVUP00000026024 | ENSVVUP00000016033 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.795 |
| ACLY | IDH2 | ENSVVUP00000026024 | ENSVVUP00000008914 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.800 |
| ACLY | IDH3A | ENSVVUP00000026024 | ENSVVUP00000001753 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.485 |
| ACLY | IDH3B | ENSVVUP00000026024 | ENSVVUP00000035638 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.522 |
| ACLY | IDH3G | ENSVVUP00000026024 | ENSVVUP00000041640 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.460 |
| ACLY | NDUFS2 | ENSVVUP00000026024 | ENSVVUP00000021478 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family. | 0.749 |
| ACLY | SDHA | ENSVVUP00000026024 | ENSVVUP00000030147 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.923 |
| ACO1 | ACLY | ENSVVUP00000028932 | ENSVVUP00000026024 | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.970 |
| ACO1 | ACO2 | ENSVVUP00000028932 | ENSVVUP00000004610 | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.921 |
| ACO1 | CS | ENSVVUP00000028932 | ENSVVUP00000030054 | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.996 |
| ACO1 | IDH1 | ENSVVUP00000028932 | ENSVVUP00000016033 | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.990 |
| ACO1 | IDH2 | ENSVVUP00000028932 | ENSVVUP00000008914 | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.990 |
| ACO1 | IDH3A | ENSVVUP00000028932 | ENSVVUP00000001753 | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.973 |
| ACO1 | IDH3B | ENSVVUP00000028932 | ENSVVUP00000035638 | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.965 |
| ACO1 | IDH3G | ENSVVUP00000028932 | ENSVVUP00000041640 | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. | 0.960 |
| ACO1 | NDUFS2 | ENSVVUP00000028932 | ENSVVUP00000021478 | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family. | 0.508 |
| ACO1 | SDHA | ENSVVUP00000028932 | ENSVVUP00000030147 | Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.687 |