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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HACE1E3 ubiquitin-protein ligase HACE1 isoform X2. (954 aa)    
Predicted Functional Partners:
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X2.
   
 
0.720
LOC112910913
Ubiquitin-like.
   
 0.688
UBC
polyubiquitin-C.
   
 0.688
UBA52
ubiquitin-60S ribosomal protein L40.
    
 0.670
ENSVVUP00000040094
annotation not available
    
 0.670
RPS27A
ubiquitin-40S ribosomal protein S27a.
   
 0.623
ENSVVUP00000014764
annotation not available
   
 0.623
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1.
    
 
 0.600
TRRAP
Transformation/transcription domain-associated protein isoform X2; Belongs to the PI3/PI4-kinase family.
   
 
 0.599
DDIT4
DNA damage-inducible transcript 4 protein.
    
   0.587
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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