close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF8Tumor necrosis factor ligand superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa)    
Predicted Functional Partners:
MIIP
Tumor necrosis factor receptor superfamily member 8.
    
 0.995
TNFSF9
Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family.
    
 
 0.530
TNFRSF1B
Tumor necrosis factor receptor superfamily member 1B.
   
 
 0.526
PROCR
Endothelial protein C receptor.
  
     0.483
TNFSF15
Tumor necrosis factor ligand superfamily member 15.
      
 0.461
NUGGC
Nuclear GTPase SLIP-GC isoform X1.
      
 0.459
RFTN2
Raftlin-2.
      
 0.459
TNFAIP6
Tumor necrosis factor-inducible gene 6 protein.
   
  
 0.455
TNFRSF25
Tumor necrosis factor receptor superfamily member 25.
      
 0.451
KITLG
Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.
  
     0.449
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.