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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCFC2GC-rich sequence DNA-binding factor 2. (740 aa)    
Predicted Functional Partners:
TFIP11
Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...]
    
 0.927
DHX15
pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15.
    
 0.895
CDC40
pre-mRNA-processing factor 17.
     
 0.828
PPIL1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
  0.816
SYF2
pre-mRNA-splicing factor SYF2.
    
  0.802
LOC112930179
pre-mRNA-splicing factor SYF2-like.
    
  0.802
RBM10
RNA-binding protein 10 isoform X1.
   
 
 0.660
ST8SIA6
Alpha-2,8-sialyltransferase 8F; Belongs to the glycosyltransferase 29 family.
   
  
 0.564
PRPF8
pre-mRNA-processing-splicing factor 8.
    
   0.563
ZPLD1
Zona pellucida-like domain-containing protein 1.
      
 0.557
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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