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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPN2Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (700 aa)    
Predicted Functional Partners:
TLN2
Talin-2 isoform X2.
   
 0.923
TLN1
Talin-1 isoform X1.
   
 0.923
CAPN1
Calpain-1 catalytic subunit isoform X1; Belongs to the peptidase C2 family.
  
 
0.920
CASP12
Caspase-12; Belongs to the peptidase C14A family.
   
 0.914
CDK5R1
Cyclin-dependent kinase 5 activator.
   
 
 0.910
BAX
Apoptosis regulator BAX isoform X2.
   
 0.907
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
  0.906
BAK1
Bcl-2 homologous antagonist/killer isoform X2.
   
 0.904
IL1A
Interleukin-1; Belongs to the IL-1 family.
   
 
 0.903
CAST
Calpastatin isoform X2.
   
 0.829
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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