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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPN8Calpain-8; Belongs to the peptidase C2 family. (406 aa)    
Predicted Functional Partners:
CAPNS1
Calpain small subunit 1.
 
 
 0.851
CAST
Calpastatin isoform X2.
   
 0.829
PLAU
Urokinase-type plasminogen activator.
   
 
 0.620
ITSN2
Intersectin-2 isoform X4.
   
 
 0.600
TXN2
Thioredoxin, mitochondrial.
   
 
 0.521
ERCC3
General transcription and DNA repair factor IIH helicase subunit XPB.
   
  
 0.515
ATF4
Cyclic AMP-dependent transcription factor ATF-4.
      
 0.506
LRGUK
Leucine-rich repeat and guanylate kinase domain-containing protein.
   
 
 0.492
MYOG
Myogenin.
   
  
 0.478
KIRREL1
Kin of IRRE-like protein 1.
     
 0.463
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.