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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINT2-2Kunitz-type protease inhibitor 2 isoform X1. (74 aa)    
Predicted Functional Partners:
HGF
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.821
TMPRSS11E
Transmembrane protease serine 11E-like; Belongs to the peptidase S1 family.
   
 0.720
MST1
Hepatocyte growth factor-like protein isoform X1; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.608
HGFAC
Hepatocyte growth factor activator isoform X3.
    
 0.586
LOC112907029
Anionic trypsin; Belongs to the peptidase S1 family.
   
 0.583
LOC112907070
Cationic trypsin; Belongs to the peptidase S1 family.
   
 0.583
ENSVVUP00000025583
annotation not available
  
 
 0.530
WFDC8
WAP four-disulfide core domain protein 8-like.
      
 0.515
RASGRP4
RAS guanyl-releasing protein 4 isoform X2.
      
 0.504
ST14
Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family.
   
 0.481
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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