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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASH1LHistone-lysine N-methyltransferase ASH1L isoform X2. (2965 aa)    
Predicted Functional Partners:
MORF4L1
Mortality factor 4-like protein 1.
   
 
 0.981
USP34
LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 34; Belongs to the peptidase C19 family.
   
 
 0.863
SETD2
Histone-lysine N-methyltransferase SETD2.
   
  
0.860
ZC3H11A
Zinc finger CCCH domain-containing protein 11A.
   
  
 0.806
MORF4L2
Mortality factor 4-like protein 2.
   
 
 0.770
PKP3
Plakophilin-3.
      
 0.768
BPTF
Nucleosome-remodeling factor subunit BPTF isoform X2.
   
 
0.766
ARID4B
LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 4B.
   
 
 0.764
MED13L
Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
  
 0.708
NIPBL
Nipped-B protein.
   
  
 0.707
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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